prime editing Archives - Made Human https://madehuman.us/tag/prime-editing/ For Healthy Communities Wed, 15 May 2024 17:34:29 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.2 https://i0.wp.com/madehuman.us/wp-content/uploads/2021/07/cropped-Icon.png?fit=32%2C32&ssl=1 prime editing Archives - Made Human https://madehuman.us/tag/prime-editing/ 32 32 194718805 New Type of Gene Editing Enters The Clinic https://madehuman.us/new-type-of-gene-editing-enters-the-clinic/ Wed, 15 May 2024 17:13:10 +0000 https://madehuman.us/?p=4083 Gene editing is difficult and, until now, has relied on different types of viral vectors to deliver a working copy of a gene into human cells. Prime, or base, editing offers a more direct way to edit human cells.

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]]> Eureka moment: April 2024 was the month when Prime Medicine announced it had convinced the FDA of the preclinical data behind prime editing to enable the first trials in humans to move forward. 

Why it matters: Gene editing is difficult and, until now, has relied on different types of viral vectors to deliver a working copy of a gene into human cells. Prime editing offers a more direct way to edit human cells.

How it’s being used now: Prime editing or base editing, as it’s sometimes known, is being explored by a number of companies, including Prime Medicine and Beam Therapeutics. 

What’s next: Early clinical data is expected to read out in 2025.

To dig deeper: https://www.nature.com/articles/s41596-022-00724-4

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